Exactly what the title says. What would the public or the comic book fans like to see more of other than what's already out? It seems that certain stories keep going and very few new topics have arisen that are worth reading. I'm currently in the process of finishing Y: The Last Man and it's got a fantastic storyline, great characters, etc. but there's only 10 books altogether. I haven't read anything vastly different in so long and I feel like the industry needs something altogether new and unheard of. I used to dream of becoming a comic book artist and writer, and it's still something I wish to accomplish, but it just feels like everything's been done. Opinions? Ideas? Suggestions?
Some of these may be obvious, some not:
Bear in mind that quite often (in fact, most of the time) the authors and artists are different people. If you're having trouble with the art side, try writing the script first and, if you find that you are having artists' block (or just have trouble drawing stick figures, like me), consider just being the writer. Of course, if you're able to do both, it's an extra selling point for whatever publisher you want to approach.
Whether superhero, reality-based, or otherwise, I'd suggest you create your own characters. Not only will this stretch you more as an author, it will avoid issues with copyrights or plans for their characters which the publisher might have that don't jibe with your story(ies).
Always be sure to protect your work before you shop it to anyone. It's a hard world out there, and you never know what greedy person might be willing to steal your ideas. At the very least, this will give you some recourse should it happen. Check out http://www.copyright.gov
and find out all you can about copyrighting original work. Getting an agent might be a good idea as well, but that may be down the road some.
Historical fiction is another avenue you might consider, similar to 300 (but obviously with a different topic). If you want to do latino characters, how about the Aztecs, Mayan Indians, Olmecs, Toltecs, Incas? Having been out of touch with the comics industry for some years, I'm not sure what's been done along that line. Even if it has been done, I'm sure you could come up with some original thoughts on the subject.